Recent Advances in Hot Melt Extrusion and its Applications

Over the decades with outcome of industrial compliance, manufacturing process, formulation and development, Hot Melt Extrusion (HME) has also expanded acceptance. As a result adaptability, it developed itself in wide range as part pharmaceutical research development. New drug entities face failures or delays during including poor biopharmaceutical properties, toxicities lack efficacy. To overcome such obstacles, HME technique is most preferred one. In comparison to conventional techniques, its use been increasing because convenient solvent free nature, cost effective on-line manufacturing. For achieving different applications several dosage forms can be produced by altering design equipment adapting modified processing condition.